Istanbul → Selçuk → Göreme puts the city first, Ephesus in the middle and Cappadocia last. Each base gets three nights: two full days between arrival and departure. Two flight days are visible parts of the ten-day plan, so an open-jaw international journey is useful. Returning to Istanbul for a separate flight may require an extra night.
Selçuk earns its three nights through early access to Ephesus, a separate museum visit and time for Ayasuluk Hill. Kuşadası offers a coastal evening, but this route prioritises archaeology over resort life. Ending in Göreme leaves one local walking day and one regional road day.
Check the İzmir–Cappadocia connection before reserving rooms. A nonstop service, when sold for your date, is simplest; a through ticket via Istanbul is another option. An overnight coach changes the nine-hotel-night plan and needs its own timetable. Pamukkale and the south coast belong in a longer trip.