Start with Barcelona’s coastal light and Modernista streets, cross to Madrid’s museums, then spend the last two nights in Andalusia. The four-city sequence follows direct rail links; Córdoba sits on the way to Seville, so its overnight introduces a different city without a backtracking excursion. You change hotels three times, however, and the short final stays demand more organisation than their train rides suggest.
The dated example runs Monday 19 to Sunday 25 October 2026. Use it when variety is your priority. Day 1 assumes an afternoon arrival in Barcelona. A late arrival leaves almost all that city to Day 2; an early morning arrival gives you a welcome bonus, rather than another promised full day. Likewise, Madrid has a transfer afternoon and one complete day. Seville offers an evening and a departure morning, not a leisurely exploration of the whole city. Book flights into Barcelona and out of Seville where practical. A compulsory return to Madrid needs a different final-night arrangement.